New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma
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چکیده
منابع مشابه
Evaluation of radiofluorinated carboximidamides as potential IDO-targeted PET tracers for cancer imaging
IDO1 is an enzyme catalyzing the initial and rate-limiting step in the catabolism of tryptophan along the kynurenine pathway. IDO1 expression could suppress immune responses by blocking T-lymphocyte proliferation locally, suggesting a role of IDO in the regulation of immune responses. The goal of this study was to evaluate the potential of radiofluorinated carboximidamides as selective PET radi...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-40013-x